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White blood cell count and the incidence of hyperuricemia: insights from a community-based study

Jian Liu, Pingyan Shen, Xiaobo Ma, Xialian Yu, Liyan Ni, Xu Hao, Weiming Wang, Nan Chen

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 741-746 doi: 10.1007/s11684-017-0579-7

Abstract: The relationship between HUA and white blood cell (WBC) count remains unknown.Patients with HUA were more likely to have higher levels of WBC count, which was positively associatedMultivariate logistic regression analysis showed that WBC count was independently associated with theHence, WBC count is positively associated with HUA, and this association is independent of conventional

Keywords： white blood cell count     hyperuricemia     chronic kidney disease     inflammation    

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Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader–Willi

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 946-956 doi: 10.1007/s11684-022-0962-x

Abstract: present study, we uncovered slight anemia in children with PWS that was associated with increased red bloodcell (RBC) distribution width (RDW) and contrarily reduced hematocrit (HCT) values.

Keywords： Prader–Willi syndrome     early diagnosis     erythrocyte deformation     membrane skeleton     membrane lipid    

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Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission

Xiaohong Shi, Xuefei Wang, Xixi Xu, Yongliang Feng, Shuzhen Li, Shuying Feng, Bo Wang, Suping Wang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 548-553 doi: 10.1007/s11684-017-0597-5

Abstract:

This study determined the effect of hepatitis B virus (HBV) replication in peripheral blood mononuclearcell (PBMC) from HBsAg-positive mothers on HBV intrauterine transmission.

Keywords： PBMC     HBV cccDNA     HBV rcDNA     HBV intrauterine transmission    

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An 84-month observational study of the changes in CD4 T-lymphocyte cell count of 110 HIV/AIDS patients

Jian Wang,Biyan Liang,Xiaoping Zhang,Liran Xu,Xin Deng,Xiuhui Li,Lu Fang,Xinghua Tan,Yuxiang Mao,Guoliang Zhang,Yuguang Wang

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 362-367 doi: 10.1007/s11684-014-0363-x

Abstract: therapeutic effect of traditional Chinese medicine (TCM) by observing the changes in CD4 T-lymphocyte cellFor CD4 count of≤200 cells/mm3, the mean CD4 count changes were 21 and 28 cells/mmFor CD4 count of 201–350 cells/mm3, the mean CD4 count changes were 6 and 25 cells/mmFor CD4 count of 351–500 cells/mm3, the mean CD4 count changes were -13 and -7 cellsFor CD4 count of>500 cells/mm3, the mean CD4 count changes were -34 and -17 cells/mm

Keywords： AIDS     HIV     CD4     traditional Chinese medicine     linear models    

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Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infraredspectroscopy: Implications for enabling cell culture process analytical technology?

Huiquan Wu, Erik Read, Maury White, Brittany Chavez, Kurt Brorson, Cyrus Agarabi, Mansoor Khan

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 3,   Pages 386-406 doi: 10.1007/s11705-015-1533-3

Abstract: Understanding process dynamics of bioreactor cell culture process is essential to establish an appropriateInline spectroscopic techniques for real time monitoring of bioreactor cell culture process have theHowever, the use of inline Fourier transform infrared (FTIR) spectroscopic techniques for bioreactor cellIn this work, real time inline FTIR Spectroscopy was applied to a lab scale bioreactor mAb IgG3 cellIts implications for enabling cell culture PAT were discussed.

Keywords： Fourier-transform infrared (FTIR) spectroscopy     partial least squares (PLS) regression     mouse IgG3     bioreactor cell    

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Non-invasive continuous blood pressure monitoring: a review of current applications

Elena Chung, Guo Chen, Brenton Alexander, Maxime Cannesson

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 91-101 doi: 10.1007/s11684-013-0239-5

Abstract:

Blood pressure monitoring has come a long way from the initial observations made by Reverend HalesThere are none that deny the importance of monitoring perioperative blood pressure; however, the limitedblood pressure measurements leaves room for improvement.Invasive monitoring is able to detect beat-to-beat blood pressure measurement, but the risks inherent, and especially the creation of those offering non-invasive but continuous blood pressure monitoring

Keywords： non-invasive blood pressure monitoring     continuous blood pressure monitoring     invasive blood pressure monitoring    

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Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 887-902 doi: 10.1007/s11684-021-0879-9

Abstract: Subarachnoid hemorrhage (SAH) induces white matter injury, but the involvement of MCT1 is unclear.this study, the SAH model of adult male Sprague-Dawley rats was used to explore the role of MCT1 in whiteoligodendrocyte MCT1 was significantly reduced, and the exogenous overexpression of MCT1 significantly improved whiteThis study confirmed that the loss of MCT1 may be one of the mechanisms of white matter damage after

Keywords： microRNAs     monocarboxylate transporter 1     motor training     subarachnoid hemorrhage     white matter injury    

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Production of a polyclonal antibody to the VP26 nucleocapsid protein of white spot syndrome virus (wssv

Suchera LOYPRASERT-THANANIMIT, Akrapon SALEEDANG, Proespichaya KANATHARANA, Panote THAVARUNGKUL, Wilaiwan CHOTIGEAT

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2,   Pages 216-223 doi: 10.1007/s11705-012-1289-y

Abstract: White spot syndrome virus (WSSV) is a major cause of high mortality in cultured shrimp all over the worldassist in recognizing its host and assists the viral nucleocapsid to move toward the nucleus of the host cell

Keywords： recombinant protein     polyclonal antibody     label-free biosensor     impedance     white spot syndrome virus (WSSV    

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Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profileand blood glucose level

TANG Zhongzhi, LI Junyao, YANG Jianhong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 178-181 doi: 10.1007/s11684-008-0033-y

Abstract: To study the relationship of the polymorphism of endothelial nitric oxide synthase (eNOS) gene and bloodpressure, lipid profiles and blood glucose level.Taking into account eNOS Glu298Asp polymorphisms, the relationship of blood pressure with triglycerides(TG), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) and bloodThe distribution of eNOS Glu298Asp polymorphism had no significant difference between different blood
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Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 420-426 doi: 10.1007/s11684-019-0688-6

Abstract: This article presents a synopsis of the current data on the mechanisms of blood—brain barrier (BBB) alterationImmune response is related to the key processes of blood clotting and fibrinolysis.

Keywords： stroke     blood–brain barrier     autoimmunity     innate immunity     inflammation     cell death    

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A microarray study of altered gene expression during melanoblasts migration in normal pigmented White

Yulin LI,Deping HAN,Junying LI,Dawn KOLTES,Xuemei DENG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 299-306 doi: 10.15302/J-FASE-2014040

Abstract: In this study, we used microarray profiling to identify differences in gene expression between Whiteexpression of 2517 microarray probes ( <0.01, Fold Change>2) was observed in Silky Fowl compared to WhiteMoreover, differences in expression of immune genes were also detected between Silky Fowl and White Leghorn

Keywords： Silky Fowl     White Leghorn     melanoblast migration     gene expression    

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control of structural responses using an optimal passive tuned mass damper under stationary Gaussian white

Min-Ho CHEY, Jae-Ung KIM

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 3,   Pages 267-280 doi: 10.1007/s11709-012-0170-x

Abstract: parameters of a TMD, such as the optimal tuning frequency and optimal damping ratio, to stationary Gaussian white

Keywords： tuned mass damper     parametric optimization     passive control     white noise     earthquake excitation    

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gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning technique as potential artificial blood

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 3,   Pages 392-400 doi: 10.1007/s11705-011-1202-0

Abstract: In this paper, a scaffold, which mimics the morphology and mechanical properties of a native blood vesselbreaking strength (3.7±0.13 MPa) and an elongation at break (110±8%) that are appropriate for artificial bloodthe complex matrix structure of native arteries, and to have good biocompatibility as an artificial blood

Keywords： electrospinning     artificial blood vessels     scaffold     polyurethane     gelatin     nanofiber     hemocompatibility    

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Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 147-151 doi: 10.1007/s11684-016-0481-8

Abstract: This study aims to investigate the mental health status of nurses exposed to blood through needlestickNo significant difference between nurses exposed to blood and nurses not exposed to blood was found inResults from the GHQ-28 Standardized Questionnaire showed that 75.9% (123/162) of nurses exposed to bloodwere suspected to suffer from mental disorders, whereas 40% (56/140) of nurses not exposed to bloodThe mean mental health scores of nurses exposed to blood and those not exposed were 8.73±7.32

Keywords： blood exposure     needlestick injuries     mental health     nurses    

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Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 336-340 doi: 10.1007/s11684-011-0163-5

Abstract: Endostatin, a 20 kDa C-terminal fragment of collagen XVIII, was first identified as a potent angiogenic inhibitor. The anti-angiogenic function of endostatin has been well documented during the past decade. Recently, several studies demonstrated that endostatin also inhibits tumor lymphangiogenesis and lymphatic metastasis. However, the exact mechanism that endostatin executes its anti-angiogenic and anti-lymphangiogenic functions remains elusive. In the current mini-review, we briefly summarize recent novel findings, including the functions of endostatin targeting not only angiogenesis but also lymphangiogenesis, and the underlying mechanism by which endostatin internalization regulates its biological functions.

Keywords： endostatin     angiogenesis     lymphangiogenesis     nystatin     internalization     tumor    

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Title Author Date Type Operation

White blood cell count and the incidence of hyperuricemia: insights from a community-based study

Jian Liu, Pingyan Shen, Xiaobo Ma, Xialian Yu, Liyan Ni, Xu Hao, Weiming Wang, Nan Chen

Journal Article

Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader–Willi

Journal Article

Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission

Xiaohong Shi, Xuefei Wang, Xixi Xu, Yongliang Feng, Shuzhen Li, Shuying Feng, Bo Wang, Suping Wang

Journal Article

An 84-month observational study of the changes in CD4 T-lymphocyte cell count of 110 HIV/AIDS patients

Jian Wang,Biyan Liang,Xiaoping Zhang,Liran Xu,Xin Deng,Xiuhui Li,Lu Fang,Xinghua Tan,Yuxiang Mao,Guoliang Zhang,Yuguang Wang

Journal Article

Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infraredspectroscopy: Implications for enabling cell culture process analytical technology?

Huiquan Wu, Erik Read, Maury White, Brittany Chavez, Kurt Brorson, Cyrus Agarabi, Mansoor Khan

Journal Article

Non-invasive continuous blood pressure monitoring: a review of current applications

Elena Chung, Guo Chen, Brenton Alexander, Maxime Cannesson

Journal Article

Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid

Journal Article

Production of a polyclonal antibody to the VP26 nucleocapsid protein of white spot syndrome virus (wssv

Suchera LOYPRASERT-THANANIMIT, Akrapon SALEEDANG, Proespichaya KANATHARANA, Panote THAVARUNGKUL, Wilaiwan CHOTIGEAT

Journal Article

Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profileand blood glucose level

TANG Zhongzhi, LI Junyao, YANG Jianhong

Journal Article

Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov

Journal Article

A microarray study of altered gene expression during melanoblasts migration in normal pigmented White

Yulin LI,Deping HAN,Junying LI,Dawn KOLTES,Xuemei DENG

Journal Article

control of structural responses using an optimal passive tuned mass damper under stationary Gaussian white

Min-Ho CHEY, Jae-Ung KIM

Journal Article

gelatin-heparin nanofibrous scaffolds formed by a bi-layer electrospinning technique as potential artificial blood

Heyun WANG, Yakai FENG, Marc BEHL, Andreas LENDLEIN, Haiyang ZHAO, Ruofang XIAO, Jian LU, Li ZHANG, Jintang GUO

Journal Article

Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Journal Article

Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Journal Article